• A bidirectional study of the association between insomnia, high-sensitivity C-reactive protein, and comorbid low back pain and lower limb pain 

      Ho, Kevin Kwan Ngai; Skarpsno, Eivind S.; Nilsen, Kristian Bernhard; Ferreira, Paulo Herrique; Pinheiro, Marina; Hopstock, Laila Arnesdatter; Johnsen, Marianne Bakke; Steingrímsdóttir, Ólöf Anna; Nielsen, Christopher Sivert; Stubhaug, Audun; Simic, Milena (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-14)
      Objectives - To examine the possible bidirectional association between insomnia and comorbid chronic low back pain (LBP) and lower limb pain and to explore whether high-sensitivity C-reactive protein (hsCRP) amplifies these associations.<p> <p>Methods - We calculated adjusted risk ratios (RR) with 95% confidence intervals (CI) for the development of insomnia and mild-to-severe chronic LBP and ...
    • Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools 

      Bahrami, Shahram; Hindley, Guy Frederick Lanyon; Winsvold, Bendik K S; O'Connell, Kevin S; Frei, Oleksandr; Shadrin, Alexey; Cheng, Weiqiu; Bettella, Francesco; Rødevand, Linn; Ødegaard, Ketil Joachim; Fan, Chun C; Pirinen, Matti J; Hautakangas, Heidi M; Martinsen, Amy; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J; Tronvik, Erling Andreas; Kristoffersen, Espen Saxhaug; Zwart, John Anker Henrik; Nielsen, Jonas Bille; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Stovner, Lars Jacob; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Lie, Marie; Holmen, Oddgeir Lingaas; Børte, Sigrid; Stensland, Synne; Zhou, Wei; Dale, Anders; Djurovic, Srdjan; Smeland, Olav Bjerkehagen; Andreassen, Ole (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-17)
      Migraine is three times more prevalent in people with bipolar disorder or depression. The relationship between schizophrenia and migraine is less certain although glutamatergic and serotonergic neurotransmission are implicated in both. A shared genetic basis to migraine and mental disorders has been suggested but previous studies have reported weak or non-significant genetic correlations and five ...
    • The Maternal and Paternal Effects on Clinically and Surgically Defined Osteoarthritis 

      Weldingh, Eirik; Johnsen, Marianne Bakke; Hagen, Kåre Birger; Østerås, Nina; Risberg, May Arna; Natvig, Bård; Christensen, Barbara Therese Slatkovsky; Fenstad, Anne Marie; Furnes, Ove; Nordsletten, Lars; Magnusson, Karin (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-25)
      <i>Objective</i> - It is currently unknown whether osteoarthritis (OA) is inherited mainly from the mother, father, or both. This study was undertaken to explore the effect of maternal and paternal factors on hip, knee, and hand OA in offspring.<p> <p><i>Methods</i> - Participants from the Musculoskeletal Pain in Ullensaker Study (MUST) (69% female; mean ± SD age 64 ± 9 years) and a Norwegian ...